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BEGIN:VEVENT
SUMMARY:Amaury Lambert (Sorbonne)
DTSTART:20201009T150000Z
DTEND:20201009T160000Z
DTSTAMP:20260404T094308Z
UID:ProbandBio/1
DESCRIPTION:Title: <a href="https://stable.researchseminars.org/talk/Proba
 ndBio/1/">Genealogy of one or many genes</a>\nby Amaury Lambert (Sorbonne)
  as part of Probability and Biology mini-series\n\n\nAbstract\nThis lectur
 e is part of the IICD & Probability and Society Initiative Joint Seminar S
 eries\, mini-series on Evolutionary processes and patterns of biodiversity
 .\n\nIn this lecture\, we explain how the genetic diversity of a sample of
  individuals can be characterized and scales with the size of the populati
 on where it is taken from\, via the study of gene genealogies and Kingman
 ’s coalescent. Next\, we display tools describing how genealogies of dif
 ferent genes are coupled by the effect of recombination. We apply these to
 ols to a practical problem (how to infer past demography given a handful o
 f genomes) and to a theoretical question (if ancestral genomes were all pa
 inted in distinct colors\, how would the mosaic of colors on the genome lo
 ok like in the long run?).\n
LOCATION:https://stable.researchseminars.org/talk/ProbandBio/1/
END:VEVENT
BEGIN:VEVENT
SUMMARY:Amaury Lambert (Sorbonne)
DTSTART:20201016T150000Z
DTEND:20201016T160000Z
DTSTAMP:20260404T094308Z
UID:ProbandBio/2
DESCRIPTION:Title: <a href="https://stable.researchseminars.org/talk/Proba
 ndBio/2/">Formation of new species</a>\nby Amaury Lambert (Sorbonne) as pa
 rt of Probability and Biology mini-series\n\n\nAbstract\nThis lecture is p
 art of the IICD & Probability and Society Initiative Joint Seminar Series\
 , mini-series on Evolutionary processes and patterns of biodiversity.\n\nT
 he evolutionary history of species can be represented by a tree called phy
 logeny. We explain how birth-death processes are standardly used to model 
 the diversification of species (speciation\, extinction) and how their par
 ameters can be inferred from the phylogeny\, notably via the so-called coa
 lescent point process. We then expose the species paradox and explain how 
 to model the formation of new species from first principles. We apply thes
 e models to an empirical question (why are species phylogenies imbalanced?
 ) and to a theoretical question (how does the graph describing the ability
  to interbreed look like?).\n
LOCATION:https://stable.researchseminars.org/talk/ProbandBio/2/
END:VEVENT
BEGIN:VEVENT
SUMMARY:Amaury Lambert (Sorbonne)
DTSTART:20201023T150000Z
DTEND:20201023T160000Z
DTSTAMP:20260404T094308Z
UID:ProbandBio/3
DESCRIPTION:Title: <a href="https://stable.researchseminars.org/talk/Proba
 ndBio/3/">Coevolving genes and species</a>\nby Amaury Lambert (Sorbonne) a
 s part of Probability and Biology mini-series\n\n\nAbstract\nThis lecture 
 is part of the IICD & Probability and Society Initiative Joint Seminar Ser
 ies\, mini-series on Evolutionary processes and patterns of biodiversity.\
 n\nDue to recombination and to hybridization between species\, the genealo
 gies of genes\, even sampled from distantly related species\, are usually 
 different at different genes\, and (so) distinct from the species tree. We
  review models coupling gene trees and species tree\, including the popula
 r multispecies coalescent. We apply these models to a practical problem (h
 ow to cluster a sample of genomes into putative species) and to a theoreti
 cal question (characterization of nested coalescents describing jointly ge
 ne trees and species tree and study of their behavior close to the present
 ).\n
LOCATION:https://stable.researchseminars.org/talk/ProbandBio/3/
END:VEVENT
BEGIN:VEVENT
SUMMARY:Alison Etheridge (Oxford)
DTSTART:20201106T160000Z
DTEND:20201106T170000Z
DTSTAMP:20260404T094308Z
UID:ProbandBio/7
DESCRIPTION:Title: <a href="https://stable.researchseminars.org/talk/Proba
 ndBio/7/">Spatial population models</a>\nby Alison Etheridge (Oxford) as p
 art of Probability and Biology mini-series\n\n\nAbstract\nThis lecture is 
 part of the IICD & Probability and Society Initiative Joint Seminar Series
 \, mini-series on Some mathematical models of evolution.\n\nHow does spati
 al structure of a population interact with genetic drift? And what about t
 he interaction with selection? We introduce some (classical and not so cla
 ssical) mathematical models that aim to capture these key forces acting on
  a population and\, as time permits\, investigate the way in which spatial
  structure influences the effectiveness of natural selection.\n
LOCATION:https://stable.researchseminars.org/talk/ProbandBio/7/
END:VEVENT
BEGIN:VEVENT
SUMMARY:Alison Etheridge (Oxford)
DTSTART:20201113T160000Z
DTEND:20201113T170000Z
DTSTAMP:20260404T094308Z
UID:ProbandBio/8
DESCRIPTION:Title: <a href="https://stable.researchseminars.org/talk/Proba
 ndBio/8/">Expanding populations</a>\nby Alison Etheridge (Oxford) as part 
 of Probability and Biology mini-series\n\n\nAbstract\nThis lecture is part
  of the IICD & Probability and Society Initiative Joint Seminar Series\, m
 ini-series on Some mathematical models of evolution.\n\nThe way in which a
  population expands its range\, or the way in which a favored genetic type
  spreads through a population\, is often modeled by the classical Fisher-K
 PP equation or its stochastic counterpart\, both of which exhibit travelin
 g wave solutions. At the front of the expanding wave\, where there is litt
 le competition for space\, individuals can reproduce quickly and produce l
 arge families. The advantage that the uncrowded nature of their environmen
 t gives them is such that they can even afford to carry some disadvantageo
 us mutations\, with the result that individuals in the front are inherentl
 y less fit than those in the bulk\, an effect called expansion load. We in
 vestigate expansion load (mostly numerically)\, particularly in the presen
 ce of genetic drift.\n
LOCATION:https://stable.researchseminars.org/talk/ProbandBio/8/
END:VEVENT
BEGIN:VEVENT
SUMMARY:Alison Etheridge (Oxford)
DTSTART:20201120T160000Z
DTEND:20201120T170000Z
DTSTAMP:20260404T094308Z
UID:ProbandBio/9
DESCRIPTION:Title: <a href="https://stable.researchseminars.org/talk/Proba
 ndBio/9/">The infinitesimal model and evolutionary rescue</a>\nby Alison E
 theridge (Oxford) as part of Probability and Biology mini-series\n\n\nAbst
 ract\nThis lecture is part of the IICD & Probability and Society Initiativ
 e Joint Seminar Series\, mini-series on Some mathematical models of evolut
 ion.\n\nMany of the classical models of natural selection acting on a popu
 lation suppose that an individual's fitness is determined by its type at s
 ome small number of genetic loci. However\, in many scenarios selection is
  acting on a trait that is determined by the accumulation of small effects
  at a very large number of loci. To model this situation\, we introduce th
 e `infinitesimal model' under which within-family trait values are normall
 y distributed (although the values across the whole population could be fa
 r from normal)\, and then use it to investigate `evolutionary rescue' - th
 e process through which maladapted individuals are able to evolve a positi
 ve growth rate fast enough to avoid extinction.\n
LOCATION:https://stable.researchseminars.org/talk/ProbandBio/9/
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